Mal-amido-PEG4-NHS ester 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
Cas No. | 756525-99-2 |
别名 | N-[15-[(2,5-二氧代-1-吡咯烷基)氧基]-15-氧代-3,6,9,12-四氧杂十五烷-1-基]-2,5-二氢-2,5-二氧代-1H-吡咯-1-丙酰胺 |
Canonical SMILES | O=C(CCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)ON2C(CCC2=O)=O |
分子式 | C22H31N3O11 |
分子量 | 513.5 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |