Biotin-PEG4-NHS ester 是一种生物素标记的 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。
| Cas No. | 459426-22-3 |
| 别名 | 21-[(3AS,4S,6AR)-六氢-2-氧代-1H-噻吩并[3,4-D]咪唑-4-基]-17-氧代-4,7,10,13-四氧杂-16-氮杂二十一碳酸2,5-二氧代-1-吡咯烷基酯 |
| Canonical SMILES | O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCNC(CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O)=O |
| 分子式 | C25H40N4O10S |
| 分子量 | 588.67 |
| 溶解度 | DMSO: 250 mg/mL (424.69 mM) |
| 储存条件 | -20°C, protect from light,unstable in solution, ready to use. |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. [1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. |
