Biotin-PEG4-alkyne 是一种生物素标记的 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
Cas No. | 1458576-00-5 |
别名 | 生物素-四聚乙二醇-丙炔基 |
Canonical SMILES | O=C(NCCOCCOCCOCCOCC#C)CCCC[C@H]1SC[C@@]([C@@]1([H])N2)([H])NC2=O |
分子式 | C21H35N3O6S |
分子量 | 457.58 |
溶解度 | DMSO: 100 mg/mL (218.54 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. [1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. |