Lobaplatin(D-19466)是铂(II)复合物的非对映混合物。Lobaplatin(D-19466)在多种肿瘤类型的患者中具有活性，是一种有前途的抗肿瘤化疗药物。
| Cas No. | 135558-11-1 |
| 别名 | 络铂; D-19466 |
| Canonical SMILES | CC1[O-][Pt+2]2([NH2]CC3C(CC3)C[NH2]2)[O-]C1=O |
| 分子式 | C9H18N2O3Pt |
| 分子量 | 397.33 |
| 溶解度 | Water: ≥ 50 mg/mL (125.84 mM; DMSO can inactivate Lobaplatin's activity) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexes. Lobaplatin (D-19466) shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2]. [1]. Cao H, et al. Lobaplatin Inhibits Prostate Cancer Proliferation and Migration Through Regulation of BCL2 and BAX. Dose Response. 2019 Jun 5;17(2):1559325819850981.
[2]. McKeage MJ, et al. Lobaplatin: a new antitumour platinum drug. Expert Opin Investig Drugs. 2001 Jan;10(1):119-28. |
