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VH 032 amide-alkylC4-amine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
VH 032 amide-alkylC4-amine图片
CAS NO:2341796-78-7
包装:25mg
市场价:2631元

VH 032 酰胺-烷基C4-胺是一种合成的 E3 连接酶配体-接头偶联物,它包含基于 (S,R,S)-AHPC 的 VHL 配体和用于 EED-Targeted PROTAC 的接头。
Cas No.2341796-78-7
别名VH032-C4-NH2 dihydrochloride
Canonical SMILESO=C(N[C@@H](C(C)(C)C)C(N1C[C@H](O)C[C@H]1C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)=O)CCCCN.Cl.Cl
分子式C27H39N5O4S.2HCl
分子量602.62
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus a short alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 3 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID:28302825

 
 
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