Sodium Houttuyfonate 是从鱼腥草中提取的天然化合物,具有抗炎、抗纤维化作用。Sodium Houttuyfonate 能通过抑制 NFκB 通路改善 LPS 诱导乳腺炎。
Cas No. | 83766-73-8 |
别名 | 鱼腥草素纳 |
Canonical SMILES | O=S(C(O)CC(CCCCCCCCC)=O)(O[Na])=O |
分子式 | C12H23NaO5S |
分子量 | 302.36 |
溶解度 | DMSO: 5 mg/mL (16.54 mM; ultrasonic and warming and heat to 60℃) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Sodium Houttuyfonate is a natural compound extracted from Houttuynia cordata, with anti-inflammatory and anti-fibrotic effects. Sodium Houttuyfonate ameliorates LPS induced mastitis by inhibiting the NF κB pathway[1][2]. [1]. Zheng C, et al. Sodium Houttuyfonate Alleviates Post-infarct Remodeling in Rats via AMP-Activated Protein Kinase Pathway. Front Pharmacol. 2018 Sep 27;9:1092.
[2]. Liu P, et al. Sodium houttuyfonate inhibits LPS?induced mastitis in mice via the NF?κB signalling pathway. Mol Med Rep. 2019 Mar;19(3):2279-2286. |