DFP00173 是一种Aquaporin-3 (AQP3)的选择性抑制剂。它对 AQP3 的选择性高于同源 AQP 亚型 AQP7 和 AQP9。它能够抑制小鼠和人 AQP3，IC50值为 ~0.1-0.4 μM。
产品描述
DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM. Compared with the homologous AQP subtypes AQP7 and AQP9, DFP00173 is selective for AQP3.
体外活性
DFP00173 inhibits the glycerol permeability of human red blood cells with IC50 of ~0.2 μM.
Cas No.
672286-03-2
分子式
C11H7Cl2N3O3S
分子量
332.16
储存和溶解度
DMSO:124 mg/mL (373.31 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
