AER-271 是一种 AER-270 的膦酸酯前药，是Aquaporin-4抑制剂，有用于急性缺血性中风的研究潜力。
产品描述
AER-271 is an inhibitor of aquaporin-4.
体内活性
Treatment with AER-271 ameliorated early cerebral edema measured at 3 h after CA vs vehicle treated rats. This treatment also attenuated early NDS. In contrast to rats treated with vehicle after CA, rats treated with AER-271 did not develop significant neuronal death or neuroinflammation as compared to sham.
Cas No.
634913-39-6
分子式
C15H9ClF6NO5P
分子量
463.65
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
