6,8-Diprenylnaringenin 是来自蛇麻草 Humulus lupulus 的天然产物。 6,8-Diprenylnaringenin 是一种乳腺癌耐药蛋白 (BCRP) 抑制剂,具有一定雌激素作用。
产品描述
6,8-Diprenylnaringenin is a natural product from hop Humulus lupulus. 6,8-Diprenylnaringenin is a breast cancer resistance protein(BCRP) inhibitor with some estrogenicity.
体外活性
6,8-Diprenylnaringenin inhibits ABCG2-mediated efflux of Mitoxantrone, and 3H-Methotrexate transport with an IC50 of 0.41 μM in HEK293 cells[1].
Cas No.
68236-11-3
分子式
C25H28O5
分子量
408.49
别名
6,8-二异戊二烯基柚皮素;Lonchocarpol A;Senegalensin
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years