Almitrine mesylate 是外周化学感受器激动剂，对Ca2+依赖性的K+通道具有选择性抑制作用。
产品描述
Almitrine dimesylate inhibits selectively the Ca2+-dependent K+ channel and that in rat chemoreceptor cells,used in the treatment of hypoxemic chronic lung diseases.
体内活性
Almitrine dimesylate is a drug used in the treatment of hypoxemic chronic lung diseases such as bronchitis and emphysema because it is a potent stimulant of the carotid bodies in human and different animal species that produces a long-lasting enhancement of alveolar ventilation, ameliorating arterial blood gases[1].
Cas No.
29608-49-9
分子式
C28H37F2N7O6S2
分子量
669.76
别名
甲磺酸阿米三嗪;Almitrine bismesylate;Almitrine dimesylate;Almitrine bismethanesulfonate
储存和溶解度
DMSO:125 mg/mL (186.63 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
