3-O-Methylgallic acid 是一种花青素代谢产物,具有强大的抗氧化能力。它还诱导细胞凋亡并具有抗癌作用,可抑制 Caco-2 细胞增殖,IC50值为 24.1 μM。
产品描述
3,4-Dihydroxy-5-methoxybenzoic acid reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3,4-Dihydroxy-5-methoxybenzoic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.
体外活性
3,4-Dihydroxy-5-methoxybenzoic acid(10-100 μM) caused a time- and dose-dependent decrease in cell viability[1].
Cas No.
3934-84-7
分子式
C8H8O5
分子量
184.15
别名
3-O-甲基没食子酸;3,4-Dihydroxy-5-methoxybenzoic acid
储存和溶解度
DMSO:37.5 mg/mL (203.64 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years