Nylidrin hydrochloride 是被动致敏大鼠腹腔肥大细胞中IgE介导的组胺释放抑制剂，具有抗过敏的功效。
| Cas No. | 849-55-8 |
| 别名 | 布芬宁盐酸盐,Buphenine hydrochloride |
| Canonical SMILES | OC(C(NC(C)CCC1=CC=CC=C1)C)C2=CC=C(O)C=C2.[H]Cl |
| 分子式 | C19H26ClNO2 |
| 分子量 | 335.87 |
| 溶解度 | DMSO: ≥ 41 mg/mL (122.07 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Nylidrin hydrochloride was an effective inhibitor of IgE-mediated release of histamine from passively sensitized rat peritoneal mast cells and human basophils, and of IgG1-mediated release of histamine from passively sensitized guinea pig lung slices. [1]. A Khandwala, et al. Antiallergic activity of nylidrin hydrochloride (RHC 3432-A). I. Effect on release of histamine in vitro from rat peritoneal mast cells, guinea pig lung slices and human basophils. International Archives of Allergy & Applied Immunology, 1983, 70 (4) |
