GNE 2861 是一种 PAK 抑制剂，具有 II 组的选择性。它抑制 PAK4、PAK5 和 PAK6 的IC50值分别为7.5、36和126 nM。
产品描述
GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.
体外活性
GNE 2861 is compound 4 in the reference.
Cas No.
1394121-05-1
分子式
C22H26N6O2
分子量
406.48
储存和溶解度
DMSO:99 mg/mL (243.55 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
