Dimethylenastron 是一种驱动蛋白Eg5抑制剂,IC50值为 200 nM。它可阻止具有单极纺锤体的细胞,所有染色体都以单极纺锤体方式附着在该纺锤体上。
产品描述
Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.
体外活性
Dimethylenastron (DMN) inhibits the growth of LECs and HUVECs in a dose- and time-dependent manner.
Cas No.
863774-58-7
分子式
C16H18N2O2S
分子量
302.39
储存和溶解度
DMSO:31 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years