RSV-IN-1 是一种有效的人呼吸道合胞病毒的抑制剂,IC50为 0.11 μM。
产品描述
RSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM.
体外活性
The concentration of P13 that reduces the number of RSV plaques (IC50 is 0.11 μM,in HEp-2 cells ). The concentration of P13 that reduces the viability of HEp-2 by CC50 is 310 μM. The selective index (CC50/IC50) values is 2818 for P13. These escape plaques are of smaller size and of non-syncytial phenotype as compared to plaques formed in the absence of inhibitor.
Cas No.
861139-16-4
分子式
C20H21N5O4S
分子量
427.48
储存和溶解度
DMSO:125 mg/mL (292.41 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years