Cetylpyridinium chloride是阳离子季铵，是一种广谱抗菌剂。它有效抑制HBV衣壳装配，IC50为 2.5 μM。它被用于杀虫剂和各种漱口水以及其他个人护理产品中。

Cetylpyridinium chloride is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.

Cetylpyridinium chloride (CPC) as active ingredient of antiseptic oral mouthrinses has a broad antimicrobial spectrum with a rapid bactericidal effect on gram-positive pathogens and a fungicide effect on yeasts in particular. Application of CPC at a concentration of 0.05% as a mouthrinse results in an immediate reduction in bacterial counts of 2.0 to 2.5 log steps (which is adequate to >99%). This reverts to about 1 log step (= 90%) 1 h after application. The ability of CPC to inhibit plaque and thereby reduce gingivitis is assured. In comparison to chlorhexidine, CPC has a lower residual effect, and as a result a lesser effect against plaque and gingivitis. The efficacy of CPC against oropharyngeal candidiasis is assured. CPC mouthrinses can significantly reduce infectious aerosols in dental practice, thereby protecting both staff and the patient. The balance of intra-oral bacterial flora is not disturbed even in the case of relatively long-term use of CPC (up to six weeks). [1]

Cetylpyridinium chloride increases the risk of severe allergic reactions, such as swelling of the mouth, face, lips or tongue, labored breathing, rashes, and hives. Ingesting high concentrations of cetylpyridinium chloride can lead to lung damage. Cetylpyridinium chloride is toxic if swallowed or inhaled. [2]

123-03-5

C21H38ClN

339.99

Hexadecylpyridinium Chloride;Pristacin;西吡氯铵;Cetamium

H2O:62 mg/mL (182.4 mM)
Ethanol:63 mg/mL (185.3 mM)
DMSO:63 mg/mL (185.3 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years