| CAS NO: | 1952247-05-0 |
| 包装: | 10mg |
| 市场价: | 2778元 |
| Cas No. | 1952247-05-0 |
| Canonical SMILES | CC1=NC(C)=C(S1)CN2C(N(C3=CC(S(=O)(NC4(CC4)C)=O)=CC=C23)C5=NC=NS5)=O |
| 分子式 | C19H20N6O3S3 |
| 分子量 | 476.59 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | High affinity and potent PARG inhibitor (Kd = 3.09 nM; IC50 = 40 nM). Negative control PDD 00031705 also available. James et al (2016) First-in-class chemical probes against poly(ADP-ribose) glycohydrolase (PARG) inhibit DNA repair with differential pharmacology to Olaparib. ACS Chem.Biol. 11 3179 PMID:27689388 |
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