位置:首页 > 产品库 > Pomalidomide 4'-PEG3-acid
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Pomalidomide 4'-PEG3-acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pomalidomide 4'-PEG3-acid图片
CAS NO:2138440-82-9
包装:25mg
市场价:1620元

Pomalidomide 4'-PEG3-acid 是一种合成的 E3 连接酶配体-接头偶联物,它包含基于 Thalidomide 的 cereblon 配体和用于 PROTAC 技术的 3 单元 PEG 接头。
Cas No.2138440-82-9
Canonical SMILESOC(CCOCCOCCOCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O
分子式C22H27N3O9
分子量477.46
溶解度Soluble in DMSO
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG3 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Pomalidomide - linker 2 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Remillard et al (2017) Degradation of the BAF complex factor BRD9 by heterobifunctional ligands. Angew.Chem.Int.Ed.Engl. 56 5738 PMID:28418626

 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024