CAS NO: | 2245697-87-2 |
包装: | 25mg |
市场价: | 1999元 |
Cas No. | 2245697-87-2 |
别名 | Thalidomide-NH-PEG2-C2-NH2 hydrochloride |
Canonical SMILES | NCCOCCOCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O.Cl |
分子式 | C19H24N4O6.HCl |
分子量 | 440.88 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG2 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Pomalidomide - linker 1 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license. Remillard et al (2017) Degradation of the BAF complex factor BRD9 by heterobifunctional ligands. Angew.Chem.Int.Ed.Engl. 56 5738 PMID:28418626 |
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