GLP-1(7-36) 是一种生理性肠降血糖素,能够刺激胰岛素分泌。
产品描述
GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays various antidiabetic effects by potentiating glucose-induced secretion of insulin from pancreatic β-cells, increasing insulin expression.
体外活性
GLP-1 secretion by human enteroendocrine NCI-H716 cells is augmented in a dose-dependent manner by the addition of CPE.
体内活性
GLP-1 secretion is compatible with the increase in observed active GLP-1(7-36) amide levels in the portal blood after administration with CPE alone in mice.
Cas No.
107444-51-9
分子式
C149H226N40O45
分子量
3297.682
别名
Glucagon-Like Peptide (GLP) I (7-36), amide, human;Human GLP-1-(7-36)-amide;GLP-1(7-36);Glucagon-like Peptide 1 (7-36) amide;MKC 253;GLP-1-(7-36)-amide;胰高血糖素样肽-1
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years