CCG-63802 是选择性的、可逆变构的G 蛋白信号调节子RGS4抑制剂。CCG-63802与RGS4特异性结合从而阻断 RGS4-Gαo相互作用，IC50为 1.9 μM。
产品描述
CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins. CCG-63802 inhibits the interaction between RGS4 and Galpha with an IC50 value of 1.4 μM.
体外活性
CCG-63802 inhibits GTPase accelerating protein activity of RGS4 and blocks its interaction with Gαo.
Cas No.
620112-78-9
分子式
C26H18N4O2S
分子量
450.51
储存和溶解度
DMSO:1.67 mg/mL (3.71 mM),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
