BD 1008 dihydrobromide 是 sigma 1 (σ1) 受体 (Ki = 2 nM) 的选择性拮抗剂。 它对 sigma1 受体具有高亲和力，对 sigma2 受体具有中等亲和力。 它通过拮抗 σ 受体减弱可卡因的毒性和刺激作用。

BD1008 dihydrobromide is a selective antagonist of the sigma 1 (σ1) receptor (Ki = 2 nM). BD1008 dihydrobromide have high affinity for sigma1 receptors, moderate affinity for sigma2 receptors. BD1008 dihydrobromide attenuate the toxicity and stimulant effects of cocaine through antagonism of sigma receptors[1].

138356-09-9

C15H24Br2Cl2N2

463.08

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years