Apalutamide-COOH可用于合成Apalutamide。Apalutamide是有效，竞争性的雄激素受体(AR)拮抗剂，IC50为16nM。
| Cas No. | 1332391-04-4 |
| Canonical SMILES | O=C(O)C1=CC=C(N(C(N(C2=CC(C(F)(F)F)=C(C#N)N=C2)C3=O)=S)C43CCC4)C=C1F |
| 分子式 | C20H12F4N4O3S |
| 分子量 | 464.39 |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Apalutamide-COOH can be used to synthesis Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1]. [1]. Nicholas D. Smith, et al. Androgen receptor modulators and uses thereof. WO2011103202A2. |
