MAC glucuronide linker-2 是一种可裂解的 ADC 连接桥,用于抗体药物结合物 (ADCs) 的合成。
Cas No. | 229977-57-5 |
Canonical SMILES | O=C(OC)[C@@H](O1)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC2=CC=C(CO)C=C2N |
分子式 | C20H25NO11 |
分子量 | 455.41 |
溶解度 | DMSO: 200 mg/mL (439.16 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. [1]. Robert A, et al. Compounds, compositions, and methods for treatment of diseases involving acidic or hypoxic diseased tissues. WO2019136298A1. |