ABT-080是白三烯合成的抑制剂，有用于治疗哮喘的潜力。
产品描述
ABT-080, a leukotriene synthesis inhibitor, is used potentially for treatment of asthma.
体外活性
ABT-080 Inhibits calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophils with IC50 of 20nM. ABT-080 inhibits LTB4 production with an IC50 of 13000nM in a calcium ionophore-stimulated human whole blood assay.
Cas No.
189498-57-5
分子式
C37H32N2NaO4
分子量
591.65
别名
VML-530;VML 530;VML530
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
