[(3S)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid;hydrobromide是一种S1P1拮抗剂,Ki=2.84 μM。
产品描述
[(3S)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid;hydrobromide is a S1P1 antagonist with Ki of 2.84 μM.
体外活性
In a GTP-gSbindingassay, activation of hS1P1 receptors by physiological agonist S1P alone or in the presence of 10 μM [(3S)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid;hydrobromide, the EC50 value was 0.8 nM or 50nM, respectively.
Cas No.
1246817-25-3
分子式
C16H28BrN2O4P
分子量
423.28
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years