Methylthiouracil 是一种抗甲状腺剂。它抑制TNF-α和IL-6的产生以及NF-Κb和ERK1/2的活化。
产品描述
Methylthiouracil is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
体外活性
Methylthiouracil acts to decrease the formation of stored thyroid hormone, as thyroglobulin in the thyroid gland. Methylthiouracil is also used in combination with radioactive iodine.
Cas No.
56-04-2
分子式
C5H6N2OS
分子量
142.18
别名
NSC-9378;甲基硫脲嘧啶;甲硫氧嘧啶;NSC-193526;MTU
储存和溶解度
DMSO:27 mg/mL (189.9 mM)
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
