(S,R,S)-AHPC-C10-NH2 dihydrochloride 包含基于 (S,R,S)-AHPC 的VHL配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物，用于合成 BET 的靶向 PROTAC。
产品描述
(S,R,S)-AHPC-C10-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker[1].
体外活性
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
2341796-75-4
分子式
C33H52ClN5O4S
分子量
650.32
别名
VH032-C10-NH2 dihydrochloride;VH032 amide-alkylC10-amine;VH032-linker 10;(S,R,S)-AHPC-C10-NH2二盐酸盐
储存和溶解度
H2O:200 mg/mL (291.21 mM)
DMSO:200 mg/mL (291.21 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
