Lipoxamycin hemisulfate 是一种丝氨酸棕榈酰转移酶抑制剂 (IC50 = 21 nM),具有抗真菌活性。
产品描述
Lipoxamycin hemisulfate is an inhibitor of serine palmitoyltransferase (IC50 = 21 nM) with antifungal activity.
体外活性
Lipoxamycin hemisulfate shows antifungal activity against a panel of human pathogenic fungi with better potency against some of the Candida species (MIC = 0.25-16 μg/mL)[1].
体内活性
In Chinese hamster ovary cell mutant, Lipoxamycin hemisulfate is highly toxic in mice when applied subeutaneously or topically[1].
Cas No.
11075-87-9
分子式
C38H74N4O14S
分子量
843.08
别名
U26146D;U-26146D;Lipoxamycin;Lipoxamycin, sulfate (2:1);U 26146D
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years