BCI hydrochloride [(E)-BCI] is a novel, potent and allosteric inhibitor of Dusp6 (dual specificity phosphatase), which acts within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. It inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively.

纯度：≥98%

CAS：95130-23-7