Nitroflurbiprofen 是一种释放 NO 的环氧合酶抑制剂，可调节门脉高压性肝硬化大鼠肝内血管张力的增加。
产品描述
Nitroflurbiprofen is a NO-releasing COX inhibitor and modulates the increased intrahepatic vascular tone in portal hypertensive cirrhotic rats.
体内活性
Nitroflurbiprofen (45 mg/kg; i.p.) improves portal hypertension without major adverse effects in thioacetamide-induced cirrhotic rats by attenuating intrahepatic vascular resistance, endothelial dysfunction, and hepatic hyperreactivity to vasoconstrictors[1].
Cas No.
158836-71-6
分子式
C19H20FNO5
分子量
361.36
别名
HCT 1206;NO-flurbiprofen;硝基氟比洛芬;Nitroxybutyl flurbiprofen
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
