Glycocholic acid 是一种胆汁酸，具有抗肿瘤活性，能够靶向作用于耐药泵和非耐药泵通路。

Glycocholic acid is a bile acid with anticancer activity. Glycocholic acid targets against pump resistance-related and non-pump resistance-related pathways.

Topoisomerase I-DNA interaction: Annealed 25-mer duplex of oligonucleotide-1 and oligonicleotide-2 is incubated with 25 or 50 units of rat liver topoisomerase I at 8 °C for 15 min in the presence or absence of betulinic acid in binding buffer. After incubation the reaction mixtures are electrophoresed in 7% non-denaturing polyacrylamide gel at 4 °C in 0.167 × TBE buffer and DNA bands are stained with ethidium bromid

475-31-0

C26H43NO6

465.631

Glycocholate;cholylglycine;甘氨胆酸

DMSO:84 mg/mL(180.4 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years