Timosaponin AIII 是一种乙酰胆碱酯酶活性抑制剂，其IC50=35.4 μM。
产品描述
Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC50: 2.5 μM, BT474 cells; 6 μM, MDAMB231). The Timosaponin AIII pro-apoptotic response is selective for tumor cells over normal cells but autophagy is induced in both.
Cas No.
41059-79-4
分子式
C39H64O13
分子量
740.928
别名
知母皂苷 A-III;Filiferin B;Timosaponin A3;AneMarsaponin A3
储存和溶解度
DMSO:135 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
