Juglone是一种从黑胡桃Juglans regia中发现的黄色染料，有抗菌作用。

Juglone is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms.

481-39-0

C10H6O3

174.15

5-羟基对萘醌;5-Hydroxy-1,4-naphthoquinone;Regianin;胡桃酮

DMSO:15 mg/mL
Ethanol:15 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years