4-HOBA 是内源性代谢产物的一种。
产品描述
4-HOBA is a less reactive isomer of 2-HOBA as well as related compounds in a mouse model of hypertension.
体内活性
4-HOBA attenuated the left ventricular (LV) and lung IsoLGs in mice after TAC. 4-HOBA attenuated TAC-induced LV hypertrophy, heart failure, and the increase of lung weight in mice, and also improved TAC-induced LV dysfunction. Moreover, 4-HOBA effectively attenuated LV cardiomyocyte hypertrophy, lung inflammation, lung fibrosis[3].
Cas No.
696-60-6
分子式
C7H9NO
分子量
123.16
别名
4-(Aminomethyl)phenol;4-HOBA;4-羟基苄胺
储存和溶解度
DMSO:50 mg/ml (406.01 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
