Glyco-Obeticholic acid is an active metabolite of Obeticholic acid formed by a phase II metabolic reaction by conjugating with amino acid glycine. Obeticholic acid (Ocaliva; 6-Ethylchenodeoxycholic acid; 6-ECDCA; INT747) is a farnesoid X receptor (FXR) agonist and semisynthetic bile acid analog (derivative of chenodeoxycholic acid) approved by FDA in 2016 to treat primary biliary cholangitis. Glyco-obeticholic acid may be used as a precursor in the preparation of bile acid analogs as agonists of the farnesoid X receptor (FXR) and TGR5.

纯度：≥98%

CAS：863239-60-5