(±)-10-HydroxycAMPtothecin 是一种从喜树茎木中分离出来的生物碱,抑制拓扑异构酶 I 活性,具有广谱抗肿瘤活性。
产品描述
(±)-10-Hydroxycamptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Cas No.
64439-81-2
分子式
C20H16N2O5
分子量
364.35
别名
10-羟基喜树碱;Hydroxy Camptothecine;10-Hydroxycamptothecin
储存和溶解度
DMSO:27 mg/mL(74.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years