Aurora Kinase inhibitor-2 是一种可渗透细胞的苯胺喹唑啉,可抑制极光激酶的活性,对Aurora A和Aurora B的IC50分别为 390 nM 和 240 nM。
产品描述
Aurora Kinase Inhibitor II is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).
体外活性
In MCF-7 cells, it blocks proliferation with an IC50 value of 1.25 M.
Cas No.
331770-21-9
分子式
C23H20N4O3
分子量
400.438
别名
Aurora Kinase Inhibitor II;IUN-70219
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years