TUG-1375 是游离脂肪酸受体 2 (FFA2/GPR43) 激动剂(pKi:6.69)。它对 FFA3，FFA4，PPARα，PPARγ，PPARδ，LXRα 或 LXRβ 无作用。
产品描述
TUG-1375 is an Agonist of Thiazolidine Free Fatty Acid Receptor 2
体外活性
TUG-1375, a compound with significantly increased potency (7-fold in a cAMP assay) and reduced lipophilicity (50-fold reduced clogP) relative to the pyrrolidine lead structure.??TUG-1375 induce human neutrophil mobilization and to inhibit lipolysis in murine adipocytes.
Cas No.
2247372-59-2
分子式
C22H19ClN2O4S
分子量
442.91
储存和溶解度
DMSO:125 mg/mL (282.22 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
