Hydroxychloroquine 是一种合成抗疟疾剂,有效抑制SARS-CoV-2感染,也抑制 Toll 样受体 7/9 信号传导。
产品描述
Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It is a medication used to prevent and treat malaria, and it's also being studied as an experimental treatment for COVID-19.
Cas No.
118-42-3
分子式
C18H26ClN3O
分子量
335.88
别名
2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol;羟氯喹
储存和溶解度
H2O:1.65 mg/mL (4.91 mM),ultrasonic and warming and heat to 60°C
DMSO:< 1 mg/mL (insoluble or slightly soluble)
1M HCl:99 mg/mL (294.75 mM),adjust pH to 2 with HCl
Powder: -20°C for 3 years
In solvent: -80°C for 2 years