Mitoquinone mesylate是可防止氧化损伤的抗氧化剂，靶向TPP的线粒体。
产品描述
Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.
体外活性
Normal rat kidney (NRK) cells exposed to CS result in a ~2-fold increase in fluorescence due to mitochondrial superoxide compared with untreated cells. Mitoquinone offers significant protection against CS-induced mitochondrial superoxide generation[1].
体内活性
Mitoquinone (MitoQ) treatment nearly doubles lung MPO activity induced by Caerulein with a significant increase of serum IL-6 levels also evident at 10?mg/kg (dose 1)[2].
Cas No.
845959-50-4
分子式
C38H47O7PS
分子量
678.81
别名
米托蒽醌甲磺酸盐;MitoQ10 mesylate;MitoQ mesylate
储存和溶解度
H2O:< 0.1 mg/mL (insoluble)
DMSO:50 mg/mL (73.66 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
