Cetirizine dihydrochloride 是羟嗪的羧化代谢物,是特异性口服有效的 H1 受体长效拮抗剂。它标记抗过敏特性,抑制过敏反应期间嗜酸性粒细胞趋化,可有效治疗过敏性鼻炎、确诊荨麻疹和花粉诱发的哮喘。
产品描述
Cetirizine dihydrochloride is an effective second-generation histamine H1 antagonist that is potent in the therapy of allergic rhinitis, confirmed urticaria, and pollen-induced asthma. Unlike other conventional antihistamines, it does not cause side effects of drowsiness or anticholinergic.
Cas No.
83881-52-1
分子式
C21H27Cl3N2O3
分子量
461.81
别名
盐酸西替利嗪;Cetirizine DiHCl;UCB P071;P071
储存和溶解度
DMSO:46.2 mg/mL (100 mM)
H2O:46.2 mg/mL (100 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years