Tesmilifene fumarate 是一种H1C受体拮抗剂，可增强化疗的细胞毒性且保护正常细胞。
产品描述
Tesmilifene fumarate (DPPE fumarate) is an H1C receptor antagonist。
体外活性
Tesmilifene may modulate the effects of 12(S)HETE in cancer cells that influence the susceptibility of cellular DNA to chemotherapy indirectly[1].
体内活性
Tesmilifene (DPPE, 20 mg/kg (s.c.) and 20 μg (icv in 5 μL)) potentiated seizures induced by both convulsants[2].
Cas No.
1185241-83-1
分子式
C23H29NO5
分子量
399.48
别名
DPPE fumarate
储存和溶解度
DMSO:248 mg/mL (620.81 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
