AZD-5069 是 CXCR2 chemokine 受体拮抗剂，用于癌症的研究。
产品描述
AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).
体外活性
AZD5069 inhibited neutrophil chemotaxis, with a pA2 of approximately 9.6, and adhesion molecule expression, with a pA2 of 6.9, in response to CXCL1[1]
Cas No.
878385-84-3
分子式
C18H22F2N4O5S2
分子量
476.51
储存和溶解度
DMSO:90 mg/mL (188.87 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
