VBY-825是CAThepsin一种新型的可逆抑制剂，对CAThepsin B, L, S和V都有很高的抑制力。
产品描述
VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.
体外活性
VBY-825 is a potent assayed cathepsins inhibitor and its potency against at least one cathepsin, cathepsin S, extends across species relevant for pharmacology studies, specifically mouse. 10 mg/kg/day dose of VBY-825 achieves a trough plasma concentration >200nM, which is well above that required for full inhibition of the intracellular activity of cathepsins B, F, K, L, S and V in both mouse and human cell lines.
Cas No.
1310340-58-9
分子式
C23H29F4N3O5S
分子量
535.55
储存和溶解度
DMSO:125 mg/mL (233.40 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
