Vicriviroc maleate 是一种可口服,可透过血脑屏障的CCR5选择性拮抗剂,同时抑制外周血单核细胞中的 HIV-1 的活性。
产品描述
Vicriviroc maleate(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment of HIV-1.
Cas No.
599179-03-0
分子式
C32H42F3N5O6
分子量
649.712
别名
SCH-D (maleate);SCH-417690 (maleate);维立韦罗马来酸盐
储存和溶解度
H2O:25 mg/mL (38.48 mM),Need ultrasonic and warming
DMSO:50 mg/mL (76.96 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years