ROCK2-IN-2 是 ROCK2 的特异性抑制剂(IC50<1 μM)。
产品描述
ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of<1 μM).
体外活性
Rho-associated protein kinase (ROCK) is a member of the serine-threonine protein kinase family including two isoforms, ROCK1 and ROCK2. ROCK2-IN-2 is involved in a number of cellular functions, which include, for example, actin organization, cell adhesion, cell migration, and cytokinesis. ROCK2-IN-2 can be used for research on the treatment of multiple medical disorders, such as fibrosis, inflammatory disorders, autoimmune disorders, and cardiovascular disorders[1].
Cas No.
1995065-79-6
分子式
C18H12N6OS
分子量
360.39
储存和溶解度
DMSO:95 mg/mL (263.60 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years