AZD7624 是一种 p38 抑制剂,具有强大的抗炎活性。
产品描述
AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.
体外活性
AZD7624 inhibits LPS-induced TNFα in human mononuclear cells, in whole blood as well as in alveolar macrophages in vitro, with pIC50s of 8.4, 8.1, and 9.0[1]. AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity.
Cas No.
1095004-78-6
分子式
C27H30FN5O3
分子量
491.56
别名
AZD-7624
储存和溶解度
DMSO:50 mg/mL (101.72 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years