Escitalopram 是一种外消旋 Citalopram 的 S-对映体,是一种选择性 5-羟色胺再摄取抑制剂,Ki=0.89 nM,比 R(-)-enantiomer 结合亲和力高 30 倍。它对多巴胺转运体和去甲肾上腺素转运体均有选择性,是一种研究抑郁症的抗抑郁药。
产品描述
Escitalopram is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition.
Cas No.
128196-01-0
分子式
C20H21FN2O
分子量
324.39
别名
Seroplex;S-(+)-Citalopram;艾司西酞普兰;依他普仑;(S)-Citalopram
储存和溶解度
DMSO:15 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years