Pramipexole 是能够透过血脑屏障的 D2 型多巴胺受体的选择性激动剂，对 D2 型受体、D2、D3、D4亚型受体的Ki分别为 2.2 nM、3.9 nM、0.5 nM、1.3 nM。它可用于研究帕金森综合症和腿多动综合征。

Pramipexole is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not been implicated in cases of clinically apparent acute liver injury.

104632-26-0

C10H17N3S

211.33

SND 919;普拉克索

H2O:<1 mgml
DMSO:39 mg/mL (184.5 mM)
Ethanol:39 mg/mL (184.5 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years